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Target Discovery and Validation
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In Vivo Mammalian Technology

Deltagen has industrialized a revolutionary in vivo technology platform for the large-scale generation of functional information on genes related to key areas of drug discovery.

Using a preferred, targeted mutagenesis process, our scientists can delete—or “knock out”—precise genes in mouse models and then utilize an extensive phenotypic analysis program to determine the specific function and potential pharmaceutical relevance of these genes and the proteins they encode. The data are consolidated in DeltaBase®, Deltagen’s premier in vivo mammalian gene function database. The proprietary technology platform has been validated through collaborations with some of the world’s leading pharmaceutical companies, including Pfizer Inc., GlaxoSmithKline plc, and Merck & Co., Inc., as well as with internationally recognized research institutions such as Stanford University.